The Binding of Isaac fangame, heavily inspired by Plants vs. Zombies
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| Status | Free Now |
| Store | itch.io |
| Genre | Strategy |
| First seen | 2026-10-21 |
| Last seen | 2026-10-21 |
I.RULE is a tower-defense fangame based on The Binding of Isaac: Rebirth, an indie roguelike designed by Edmund McMillen and developed and published by Nicalis. This game is my tribute to Ed and George Fan, authors of Basement Collection and Plants vs. Zombies, whose game mechanics I tried to combine in this "crossover", if you can call it that. It's a roguelite where you fight monsters using babies with different abilities, based on familiars from The Binding of Isaac. Fight bosses, complete various challenges and craft the most effective strategy to win! And if you haven't played TBoI or…
| Genre | Strategy |
| Rating | ★ 4.9 · 499 ratings |
| Developer | DoctorHummer, toncho_ |
Source: itch.io game page